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Peptide record

TPDB10107

Antibacterial Antifungal Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10107
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLKKIFKAGLGSLVKGIAAHVAS
Physicochemical Analysis
C105H181N29O26
RNDCEQMPTWY
AGK
2265.77
11.00
5
0
12
+4
1.25
0.730
127.39
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
1
H
2
I
3
L
4
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C105H181N29O26
2265.77
11.00
+4
1.25
0.730
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
50% Hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent and rapid bactericidal action of alyteserin-1c and its [E4K] analog against multidrug-resistant strains of Acinetobacter baumannii. | Peptides | 2010
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
50% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent and rapid bactericidal action of alyteserin-1c and its [E4K] analog against multidrug-resistant strains of Acinetobacter baumannii. | Peptides | 2010
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis