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Peptide record

TPDB10104

Antibacterial Antifungal standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10104
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 23-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
ITIPPIVKDTLKKFIKGAISSVM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C117H203N27O30S1
RNCEQHWY
I
2500.12
10.55
4
1
11
+3
-0.12
0.674
131.30
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
5
I
1
L
4
K
1
M
1
F
2
P
2
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 5 L: 1 K: 4 M: 1 F: 1 P: 2 S: 2 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
23 reviewed residue count
C117H203N27O30S1 sequence-only estimate (linear, free termini)
2500.12 sequence-only estimate (linear, free termini)
10.55 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
-0.12 sequence-only estimate (linear, free termini)
0.674 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against S. aureus (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
20 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 20 uM).