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Peptide record

TPDB10103

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10103
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GVGKFLHSAKKFGQALASEIMKS
Physicochemical Analysis
C110H180N30O30S1
RNDCPTWY
K
2434.88
10.55
5
1
10
+3
3.58
-0.009
76.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
1
E
1
Q
3
G
1
H
1
I
2
L
4
K
1
M
2
F
0
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 1 I: 1 L: 2 K: 4 M: 1 F: 2 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C110H180N30O30S1
2434.88
10.55
+3
3.58
-0.009
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae) | Comp Biochem Physiol C Toxicol Pharmacol | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis