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Peptide record

TPDB10100

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10100
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF APD_hemolytic
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLVTGLLKTAGKLLGDLFGSLTG
Physicochemical Analysis
C102H175N25O30
RNCEQHIMPWY
L
2231.66
9.88
2
1
10
+1
-1.33
0.817
135.65
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
6
G
0
H
0
I
7
L
2
K
0
M
1
F
0
P
1
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 6 H: 0 I: 0 L: 7 K: 2 M: 0 F: 1 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C102H175N25O30
2231.66
9.88
+1
-1.33
0.817
Evidence Records 3 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
22 48 %
[Ref.17128968]22% hemolytic at 50 µM, 48% hemolytic activity at 100 µM against rat red blood cells

Target

rat red blood cells

Source & Reference

APD_hemolytic
DRAMP4
Biochemistry 2006 45: 14285-14297.

Other

Source Activity Label Source Definition
Hemolysis
APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.17128968]22% hemolytic at 50 µM, 48% hemolytic activity at 100 µM against rat red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochemistry 2006 45: 14285-14297.
Evidence 3 Hemolysis

Activity

22 48 %
% Hemolysis
[Ref.17128968]22% hemolytic at 50 µM, 48% hemolytic activity at 100 µM against rat red blood cells
Hemolysis

Target

rat red blood cells

Source & Reference

APD_hemolytic
Biochemistry 2006 45: 14285-14297.
DRAMP4
APD_hemolytic