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Peptide record

TPDB10098

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10098
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIGKHVGKALKGLKGLLKGLGES
Physicochemical Analysis
C102H182N30O27
RNDCQMFPTWY
G
2260.75
10.71
6
1
8
+4
4.92
-0.013
118.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
7
G
1
H
1
I
5
L
5
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 7 H: 1 I: 1 L: 5 K: 5 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C102H182N30O27
2260.75
10.71
+4
4.92
-0.013
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>800 µM
Hemolytic Cytotoxic
50% Hemolysis | >800 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Computational design of highly selective antimicrobial peptides. | J Chem Inf Model | 2009
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 3 Activity

Activity

HC50
Toxicity
800 µM
Hemolytic
Hemolytic_activity: [Ref.19947578] HC50>800 µM against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Chem Inf Model. 2009 Dec 49(12):2873-82