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Peptide record

TPDB10097

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10097
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VFHLLGKIIHHVGNFVYGFSHVF
Physicochemical Analysis
C132H187N33O27
ARDCEQMPTW
HFV
2668.14
9.74
5
0
13
+1
-1.51
0.917
118.26
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
55.84
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
4
H
2
I
2
L
1
K
0
M
4
F
0
P
1
S
0
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 2 L: 2 K: 1 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 4
Chemical Descriptors
23
C132H187N33O27
2668.14
9.74
+1
-1.51
0.917
Evidence Records 3 records
Evidence 1 Activity

Activity

47% Cell death
Toxicity
128 µg/mL
Cytotoxic
47% Cell death | 128 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021
Evidence 2 Activity

Activity

30% Cell death
Toxicity
128 µg/mL
Cytotoxic
30% Cell death | 128 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021
Evidence 3 Activity

Activity

0% Cell death
Toxicity
64 µg/mL
Cytotoxic
0% Cell death | 64 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021