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Peptide record

TPDB10084

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10084
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGKFAHSAKKFGKAFVGEIMNS
Physicochemical Analysis
C111H174N30O29S1
RDCQLPTWY
GK
2424.85
10.55
5
1
10
+3
2.98
-0.004
59.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
0
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 0 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C111H174N30O29S1
2424.85
10.55
+3
2.98
-0.004
Evidence Records 2 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015