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Peptide record

TPDB10081

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10081
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
FLRFAGSVIHGAGHLVHHIGVAL
Physicochemical Analysis
C113H174N34O25
NDCEQKMPTWY
GH
2408.84
11.05
5
0
13
+1
-0.04
1.057
135.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
4
H
2
I
3
L
0
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 4 I: 2 L: 3 K: 0 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C113H174N34O25
2408.84
11.05
+1
-0.04
1.057
Evidence Records 4 records
Evidence 1 Activity

Activity

EC50
Toxicity
>400 µM
Cytotoxic
EC50 | >400 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
10% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
334 µM
Hemolytic Cytotoxic
50% Hemolysis | 334 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis