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Peptide record

TPDB10074

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10074
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVVTDLLNTAGGLLGNLVGSLSG
Physicochemical Analysis
C92H159N25O32
RCEQHIKMFPWY
GL
2127.42
3.10
0
1
10
-1
-0.65
0.926
143.91
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
1
A
0
R
2
N
1
D
0
C
0
E
0
Q
6
G
0
H
0
I
6
L
0
K
0
M
0
F
0
P
2
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 6 H: 0 I: 0 L: 6 K: 0 M: 0 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C92H159N25O32
2127.42
3.10
-1
-0.65
0.926
Evidence Records 3 records
Evidence 1 Activity

Activity

42% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
42% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
The plasticins: membrane adsorption, lipid disorders, and biological activity. | Biochemistry | 2006
Evidence 2 Activity

Activity

75% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
75% Hemolysis | 100 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
The plasticins: membrane adsorption, lipid disorders, and biological activity. | Biochemistry | 2006
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.