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Peptide record

TPDB10073

Antibacterial Anticancer Antifungal Antiparasitic standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10073
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LPFVAGVAAEMMQHVYCAASKKC
Physicochemical Analysis
C108H172N28O29S4
RNDITW
A
2454.96
8.28
3
1
13
+1
1.92
0.648
76.52
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1615
65.79
5
Residue Composition
number
5
A
0
R
0
N
0
D
2
C
1
E
1
Q
1
G
1
H
0
I
1
L
2
K
2
M
1
F
1
P
1
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 2 E: 1 Q: 1 G: 1 H: 1 I: 0 L: 1 K: 2 M: 2 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
23
C108H172N28O29S4
2454.96
8.28
+1
1.92
0.648
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.3 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
10.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
10.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
5.3 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
10.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
10.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.3 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
10.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.3 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
10.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 42.4 ug/ml), Gram+ bacteria S. aureus (MIC 10.6 ug/ml), and yeast C. albicans (MIC 10.6 ug/ml). Updated 7/2021