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Peptide record

TPDB10071

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10071
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept i2APP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GVSKILHSAGKFGKAFLGEIMKS
Physicochemical Analysis
C110H181N29O29S1
RNDCQPTWY
GK
2405.88
10.55
5
1
10
+3
2.87
0.243
89.13
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
2
L
4
K
1
M
2
F
0
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 2 K: 4 M: 1 F: 2 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C110H181N29O29S1
2405.88
10.55
+3
2.87
0.243
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Escherichia coli pnly weakly

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli pnly weakly (MIC 100 uM). Additional 11 new peptides were reported and their antimicrobial activity remains establ
Evidence 2 Activity

Activity

MIC
Antifungal
100 µM

Target

Escherichia coli pnly weakly

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli pnly weakly (MIC 100 uM). Additional 11 new peptides were reported and their antimicrobial activity remains establ
Evidence 3 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Escherichia coli pnly weakly

Source & Reference

NA

Other

Active against E. coli pnly weakly (MIC 100 uM). Additional 11 new peptides were reported and their antimicrobial activity remains establ
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Orthologs of magainin, PGLa, procaerulein-derived, and proxenopsin-derived peptides from skin secretions of the octoploid frog Xenopus amieti (Pipidae). | Peptides | 2010
Evidence 5 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.