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Peptide record

TPDB10070

Antibacterial Antifungal standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10070
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WGFCWNVCVYRNGVRVCHRRCN
Physicochemical Analysis
C118H175N41O27S4
ADEQILKMPST
RCV
2728.19
9.27
5
0
8
+4
-0.97
-0.273
52.73
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
12740
466.98
8
Residue Composition
number
0
A
4
R
3
N
0
D
4
C
0
E
0
Q
2
G
1
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
2
W
1
Y
4
V
Amino Acid Distribution
A: 0 R: 4 N: 3 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 4
Chemical Descriptors
22
C118H175N41O27S4
2728.19
9.27
+4
-0.97
-0.273
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/m
Evidence 2 Activity

Activity

MIC
Antibacterial
0.25 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP

Other

15 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP

Other

ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Pseudomonas aeruginosa CICC21630

Source & Reference

dbAMP

Other

enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1
Evidence 5 Activity

Activity

MIC
Antibacterial
1-8 µg/mL

Target

Staphylococcus aureus ATCC43300 MRSA or ATCC25923

Source & Reference

dbAMP

Other

llorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP

Other

osa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/m
Evidence 8 Activity

Activity

MIC
Antifungal
0.25 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP CAFPdb Antifungipept

Other

15 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml),
Evidence 9 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), S. typhimurium ATCC14028 (MIC 2 ug/ml), S. enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC
Evidence 10 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Pseudomonas aeruginosa CICC21630

Source & Reference

dbAMP CAFPdb Antifungipept

Other

enteritidis CVCC3377 (MIC 0.25 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1
Evidence 11 Activity

Activity

MIC
Antifungal
1-8 µg/mL

Target

Staphylococcus aureus ATCC43300 MRSA or ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

llorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), P. aeruginosa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

osa CICC21630 (MIC 4 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 1-8 ug/ml), B. subtilis ATCC6633 (MIC 1 ug/ml).