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Peptide record

TPDB10048

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10048
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGGALLSAGKAALKGLAKVLV
Physicochemical Analysis
C92H167N25O24
RNDCEQHMFPTWY
AGL
2007.49
10.84
3
0
13
+3
-0.67
1.200
155.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
1
I
5
L
3
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 1 L: 5 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C92H167N25O24
2007.49
10.84
+3
-0.67
1.200
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtil
Evidence 2 Activity

Activity

MIC
Antibacterial
9.4 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

l are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

ude Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
9.4 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
18.8 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtil
Evidence 6 Activity

Activity

MIC
Antifungal
9.4 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

l are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ude Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
9.4 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
18.8 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

NA

Other

peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtil
Evidence 10 Activity

Activity

MIC
Antiparasitic
9.4 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

l are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

ude Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiparasitic
9.4 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiviral
18.8 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

NA

Other

peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtil
Evidence 14 Activity

Activity

MIC
Antiviral
9.4 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

l are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 15 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

ude Fungus C. albicans ATCC 20032 (MIC 18.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 16 Activity

Activity

MIC
Antiviral
9.4 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

.8 ug/ml), S. aureus ATCC 25923 (MIC 9.4 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B. subtilis ATCC 6633 (MIC 9.4 ug/ml).
Evidence 17 Activity

Activity

45% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
45% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 18 Activity

Activity

28% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
28% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 19 Activity

Activity

27% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
27% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 20 Activity

Activity

15% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 21 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.