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Peptide record

TPDB10044

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10044
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb i2APP AI4AVP dbAMP 3.0 DRAVP 2.0 APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FFHHIFRGIVHVGKTIHKLVTG
Physicochemical Analysis
C122H187N35O25
ANDCEQMPSWY
H
2544.05
11.64
7
0
10
+3
2.27
0.482
110.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
3
I
1
L
2
K
0
M
3
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 3 L: 1 K: 2 M: 0 F: 3 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C122H187N35O25
2544.05
11.64
+3
2.27
0.482
Evidence Records 39 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.46 µM

Target

S. iniae

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
0.61 µM

Target

L. garvieae

Source & Reference

dbAMP DRAMP

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis
Evidence 3 Activity

Activity

MIC
Antibacterial
4.91 µM

Target

V. anguillarum

Source & Reference

dbAMP DRAMP

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
1.23 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

IC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minim
Evidence 5 Activity

Activity

MIC
Antibacterial
2.46 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentr
Evidence 6 Activity

Activity

MIC
Antibacterial
2.46 µM

Target

S. flexneri

Source & Reference

dbAMP DRAMP

Other

cida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It
Evidence 7 Activity

Activity

MIC
Antibacterial
4.91 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

hogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It is also active against chan
Evidence 8 Activity

Activity

MIC
Antifungal
2.46 µM

Target

S. iniae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM),
Evidence 9 Activity

Activity

MIC
Antifungal
0.61 µM

Target

L. garvieae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis
Evidence 10 Activity

Activity

MIC
Antifungal
4.91 µM

Target

V. anguillarum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antifungal
1.23 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minim
Evidence 12 Activity

Activity

MIC
Antifungal
2.46 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentr
Evidence 13 Activity

Activity

MIC
Antifungal
2.46 µM

Target

S. flexneri

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

cida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It
Evidence 14 Activity

Activity

MIC
Antifungal
4.91 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

hogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It is also active against chan
Evidence 15 Activity

Activity

MIC
Antiparasitic
2.46 µM

Target

S. iniae

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM),
Evidence 16 Activity

Activity

MIC
Antiparasitic
0.61 µM

Target

L. garvieae

Source & Reference

dbAMP 3.0 DRAMP

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis
Evidence 17 Activity

Activity

MIC
Antiparasitic
4.91 µM

Target

V. anguillarum

Source & Reference

dbAMP 3.0 DRAMP

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC
Evidence 18 Activity

Activity

MIC
Antiparasitic
1.23 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

IC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minim
Evidence 19 Activity

Activity

MIC
Antiparasitic
2.46 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

(MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentr
Evidence 20 Activity

Activity

MIC
Antiparasitic
2.46 µM

Target

S. flexneri

Source & Reference

dbAMP 3.0 DRAMP

Other

cida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It
Evidence 21 Activity

Activity

MIC
Antiparasitic
4.91 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP

Other

hogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It is also active against chan
Evidence 22 Activity

Activity

MIC
Antiviral
2.46 µM

Target

S. iniae

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM),
Evidence 23 Activity

Activity

MIC
Antiviral
0.61 µM

Target

L. garvieae

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis
Evidence 24 Activity

Activity

MIC
Antiviral
4.91 µM

Target

V. anguillarum

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

fish pathogens S. iniae (MIC 2.46 uM), L. garvieae (MIC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC
Evidence 25 Activity

Activity

MIC
Antiviral
1.23 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

IC 0.61 uM), V. anguillarum (MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minim
Evidence 26 Activity

Activity

MIC
Antiviral
2.46 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

(MIC 4.91 uM), A-salmonicida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentr
Evidence 27 Activity

Activity

MIC
Antiviral
2.46 µM

Target

S. flexneri

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

cida (MIC >78.61 uM), human pathogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It
Evidence 28 Activity

Activity

MIC
Antiviral
4.91 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

hogens E. faecalis (MIC 1.23 uM), S. aureus (MIC 2.46 uM), S. flexneri (MIC 2.46 uM), and E. coli (MIC 4.91 uM). Its minimum parasiticidal concentrations (PC100 2.48 uM). It is also active against chan
Evidence 29 Activity

Activity

0% Hemolysis
Toxicity
1.25 µM
Hemolytic Cytotoxic
0% Hemolysis | 1.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 30 Activity

Activity

1% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
1% Hemolysis | 2.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 31 Activity

Activity

19% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
19% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 32 Activity

Activity

55% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
55% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 33 Activity

Activity

100% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
100% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 34 Activity

Activity

0% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
0% Hemolysis | 5 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 35 Activity

Activity

11% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
11% Hemolysis | 10 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 36 Activity

Activity

51% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
51% Hemolysis | 20 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 37 Activity

Activity

80% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
80% Hemolysis | 40 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 38 Activity

Activity

100% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
100% Hemolysis | 80 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. | J Biol Chem | 2002
Evidence 39 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.