Back to search

Peptide record

TPDB10042

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10042
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GMATKAGTALGKVAKAVIGAAL
Physicochemical Analysis
C88H159N25O25S1
RNDCEQHFPSWY
A
1999.44
10.84
3
0
13
+3
0.58
0.923
111.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
7
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
2
L
3
K
1
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 3 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C88H159N25O25S1
1999.44
10.84
+3
0.58
0.923
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
80 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
160 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
80 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
160 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
80 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
160 µM

Target

S.aureus

Source & Reference

DRAMP

Other

weakly active against E. coli (MIC 80 uM) and S.aureus (MIC 160 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
>160 µM
Hemolytic Cytotoxic
50% Hemolysis | >160 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). | Peptides | 2012
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
>150 µM
Hemolytic Cytotoxic
50% Hemolysis | >150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae). | Biochim Biophys Acta | 2001
Evidence 9 Activity

Activity

HC50
Toxicity
150 µM
Hemolytic
Hemolytic_activity: [Ref.11738090]HC50>150 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2001 Nov 26 1550(1):81-89.