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Peptide record

TPDB10041

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10041
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVFLDALKKFAKGGMNAVLNPK
Physicochemical Analysis
C107H176N28O27S1
RCEQHISTWY
K
2318.81
10.55
4
1
11
+3
1.97
0.173
93.18
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
0
R
2
N
1
D
0
C
0
E
0
Q
3
G
0
H
0
I
3
L
4
K
1
M
2
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 3 K: 4 M: 1 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C107H176N28O27S1
2318.81
10.55
+3
1.97
0.173
Evidence Records 4 records
Evidence 1 Activity

Activity

HC50
Hemolysis
150 µM
[Ref.11738090]HC50>150 µM against human erythrocytes

Target

human erythrocytes

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Biochim Biophys Acta. 2001 Nov 26 1550(1):81-89.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>150 µM
Hemolytic Cytotoxic
50% Hemolysis | >150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae). | Biochim Biophys Acta | 2001
Evidence 3 Activity

Activity

HC50
Toxicity
150 µM
Hemolytic
Hemolytic_activity: [Ref.11738090]HC50>150 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2001 Nov 26 1550(1):81-89.
Evidence 4 Hemolysis

Activity

150 µM
HC50
[Ref.11738090]HC50>150 µM against human erythrocytes
Hemolysis

Target

human erythrocytes

Source & Reference

APD_complete HemoPI PD_Hemolysis
Biochim Biophys Acta. 2001 Nov 26 1550(1):81-89.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.