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Peptide record

TPDB10039

Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10039
Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 dbAMP DRAMP ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb i2APP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Anticancer, and other sources) peptide sequence curated from Peptipedia, AntiBP3, dbAMP, and other sources, with an available 3D structural model.
Sequence
GIGKFLKKAKKFGKAFVKILKK
Physicochemical Analysis
C122H209N31O23
RNDCEQHMPSTWY
K
2478.20
11.41
9
0
10
+9
3.54
-0.159
93.18
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
2
L
9
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 9 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C122H209N31O23
2478.20
11.41
+9
3.54
-0.159
Evidence Records 133 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Acinetobacter spp.

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
tested at a break-point of 64 ug/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freu
Evidence 2 Activity

Activity

MIC
Antibacterial
4-64 µg/mL

Target

Alcaligenes faecalis

Source & Reference

dbAMP DRAMP

Other

g/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. j
Evidence 3 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Citrobacter diversus

Source & Reference

dbAMP DRAMP

Other

nst Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes
Evidence 4 Activity

Activity

MIC
Antibacterial
8->256 µg/mL

Target

Citrobacter freundii

Source & Reference

dbAMP DRAMP

Other

ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25
Evidence 5 Activity

Activity

MIC
Antibacterial
0.125-4 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP DRAMP

Other

/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.fae
Evidence 6 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Enterobacter aerogenes

Source & Reference

dbAMP DRAMP

Other

8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli
Evidence 7 Activity

Activity

MIC
Antibacterial
1-128 µg/mL

Target

Enterobacter cloacae

Source & Reference

dbAMP DRAMP

Other

8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca
Evidence 8 Activity

Activity

MIC
Antibacterial
>256 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

g/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoni
Evidence 9 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. ae
Evidence 10 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Klebsiella oxytoca

Source & Reference

dbAMP DRAMP

Other

-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P.
Evidence 11 Activity

Activity

MIC
Antibacterial
8-32 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

>256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P.
Evidence 12 Activity

Activity

MIC
Antibacterial
8-32 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

g/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aure
Evidence 13 Activity

Activity

MIC
Antibacterial
2-8 µg/mL

Target

Pseudomonas fluorescens

Source & Reference

dbAMP DRAMP

Other

l), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. a
Evidence 14 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Pseudomonas stutzeri

Source & Reference

dbAMP DRAMP

Other

ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/
Evidence 15 Activity

Activity

MIC
Antibacterial
16-64 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP DRAMP

Other

ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 u
Evidence 16 Activity

Activity

MIC
Antibacterial
0.125-16 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP DRAMP

Other

/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml
Evidence 17 Activity

Activity

MIC
Antibacterial
0.125-8 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. sim
Evidence 18 Activity

Activity

MIC
Antibacterial
408 µg/mL

Target

Staphylococcus haemolyticus

Source & Reference

dbAMP DRAMP

Other

reus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warn
Evidence 19 Activity

Activity

MIC
Antibacterial
2-8 µg/mL

Target

Staphylococcus hominis

Source & Reference

dbAMP DRAMP

Other

. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S.
Evidence 20 Activity

Activity

MIC
Antibacterial
0.125-2 µg/mL

Target

Staphylococcus simulans

Source & Reference

dbAMP DRAMP

Other

ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less),
Evidence 21 Activity

Activity

MIC
Antibacterial
0.125-8 µg/mL

Target

Staphylococcus warneri

Source & Reference

dbAMP DRAMP

Other

ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml
Evidence 22 Activity

Activity

MIC
Antibacterial
4-16 µg/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP DRAMP

Other

S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equi
Evidence 23 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Streptococcus agalactiae

Source & Reference

dbAMP DRAMP

Other

. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes
Evidence 24 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Streptococcus bovis

Source & Reference

dbAMP DRAMP

Other

, S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Strept
Evidence 25 Activity

Activity

MIC
Antibacterial
2-16 µg/mL

Target

Streptococcus equinus

Source & Reference

dbAMP DRAMP

Other

ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug
Evidence 26 Activity

Activity

MIC
Antibacterial
16-256 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP

Other

16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug/ml), Streptococcus group G 5 strains (MIC
Evidence 27 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Bacteroides fragilis

Source & Reference

dbAMP DRAMP

Other

/ml), Viridans group streptococci 13 strains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vu
Evidence 28 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Bacteroides ovatus

Source & Reference

dbAMP DRAMP

Other

rains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. di
Evidence 29 Activity

Activity

MIC
Antibacterial
0.25-0.5 µg/mL

Target

Bacteroides ureolyticus

Source & Reference

dbAMP DRAMP

Other

bic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfri
Evidence 30 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Bacteroides vulgatus

Source & Reference

dbAMP DRAMP

Other

g/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C.
Evidence 31 Activity

Activity

MIC
Antibacterial
0.5-4 µg/mL

Target

Clostridioides difficile

Source & Reference

dbAMP DRAMP

Other

g/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporo
Evidence 32 Activity

Activity

MIC
Antibacterial
8-32 µg/mL

Target

Clostridium perfringens

Source & Reference

dbAMP DRAMP

Other

.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridiu
Evidence 33 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Clostridium ramosum

Source & Reference

dbAMP DRAMP

Other

ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6
Evidence 34 Activity

Activity

MIC
Antibacterial
8-32 µg/mL

Target

Clostridium sporogenes

Source & Reference

dbAMP DRAMP

Other

4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharol
Evidence 35 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Peptostreptococcus anaerobius

Source & Reference

dbAMP DRAMP

Other

(MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml),
Evidence 36 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Peptostreptococcus asaccharolyticus

Source & Reference

dbAMP DRAMP

Other

IC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. m
Evidence 37 Activity

Activity

MIC
Antibacterial
0.5-1.0 µg/mL

Target

Peptostreptococcus magnus

Source & Reference

dbAMP DRAMP

Other

P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml)
Evidence 38 Activity

Activity

MIC
Antibacterial
32-128 µg/mL

Target

Prevotella bivia

Source & Reference

dbAMP DRAMP

Other

, P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64-
Evidence 39 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Prevotella melaninogenica

Source & Reference

dbAMP DRAMP

Other

/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histi
Evidence 40 Activity

Activity

MIC
Antibacterial
64->512 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

ia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histiocytic cell line (tumor).
Evidence 41 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Acinetobacter spp.

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
tested at a break-point of 64 ug/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freu
Evidence 42 Activity

Activity

MIC
Antifungal
4-64 µg/mL

Target

Alcaligenes faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. j
Evidence 43 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Citrobacter diversus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

nst Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes
Evidence 44 Activity

Activity

MIC
Antifungal
8->256 µg/mL

Target

Citrobacter freundii

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25
Evidence 45 Activity

Activity

MIC
Antifungal
0.125-4 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.fae
Evidence 46 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Enterobacter aerogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli
Evidence 47 Activity

Activity

MIC
Antifungal
1-128 µg/mL

Target

Enterobacter cloacae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca
Evidence 48 Activity

Activity

MIC
Antifungal
>256 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoni
Evidence 49 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. ae
Evidence 50 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Klebsiella oxytoca

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P.
Evidence 51 Activity

Activity

MIC
Antifungal
8-32 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

>256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P.
Evidence 52 Activity

Activity

MIC
Antifungal
8-32 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aure
Evidence 53 Activity

Activity

MIC
Antifungal
2-8 µg/mL

Target

Pseudomonas fluorescens

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

l), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. a
Evidence 54 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Pseudomonas stutzeri

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/
Evidence 55 Activity

Activity

MIC
Antifungal
16-64 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 u
Evidence 56 Activity

Activity

MIC
Antifungal
0.125-16 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml
Evidence 57 Activity

Activity

MIC
Antifungal
0.125-8 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. sim
Evidence 58 Activity

Activity

MIC
Antifungal
408 µg/mL

Target

Staphylococcus haemolyticus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

reus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warn
Evidence 59 Activity

Activity

MIC
Antifungal
2-8 µg/mL

Target

Staphylococcus hominis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S.
Evidence 60 Activity

Activity

MIC
Antifungal
0.125-2 µg/mL

Target

Staphylococcus simulans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less),
Evidence 61 Activity

Activity

MIC
Antifungal
0.125-8 µg/mL

Target

Staphylococcus warneri

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml
Evidence 62 Activity

Activity

MIC
Antifungal
4-16 µg/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equi
Evidence 63 Activity

Activity

MIC
Antifungal
16-32 µg/mL

Target

Streptococcus agalactiae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes
Evidence 64 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Streptococcus bovis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Strept
Evidence 65 Activity

Activity

MIC
Antifungal
2-16 µg/mL

Target

Streptococcus equinus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug
Evidence 66 Activity

Activity

MIC
Antifungal
16-256 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug/ml), Streptococcus group G 5 strains (MIC
Evidence 67 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Bacteroides fragilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), Viridans group streptococci 13 strains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vu
Evidence 68 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Bacteroides ovatus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

rains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. di
Evidence 69 Activity

Activity

MIC
Antifungal
0.25-0.5 µg/mL

Target

Bacteroides ureolyticus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

bic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfri
Evidence 70 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Bacteroides vulgatus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C.
Evidence 71 Activity

Activity

MIC
Antifungal
0.5-4 µg/mL

Target

Clostridioides difficile

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporo
Evidence 72 Activity

Activity

MIC
Antifungal
8-32 µg/mL

Target

Clostridium perfringens

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridiu
Evidence 73 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Clostridium ramosum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6
Evidence 74 Activity

Activity

MIC
Antifungal
8-32 µg/mL

Target

Clostridium sporogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharol
Evidence 75 Activity

Activity

MIC
Antifungal
32-64 µg/mL

Target

Peptostreptococcus anaerobius

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml),
Evidence 76 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Peptostreptococcus asaccharolyticus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. m
Evidence 77 Activity

Activity

MIC
Antifungal
0.5-1.0 µg/mL

Target

Peptostreptococcus magnus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml)
Evidence 78 Activity

Activity

MIC
Antifungal
32-128 µg/mL

Target

Prevotella bivia

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64-
Evidence 79 Activity

Activity

MIC
Antifungal
32-64 µg/mL

Target

Prevotella melaninogenica

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histi
Evidence 80 Activity

Activity

MIC
Antifungal
64->512 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histiocytic cell line (tumor).
Evidence 81 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Acinetobacter spp.

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
tested at a break-point of 64 ug/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freu
Evidence 82 Activity

Activity

MIC
Antiparasitic
4-64 µg/mL

Target

Alcaligenes faecalis

Source & Reference

DRAMP

Other

g/ml ( Fucks et al., 1998 ). Active against Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. j
Evidence 83 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Citrobacter diversus

Source & Reference

DRAMP

Other

nst Acinetobacter sp. 10 strains (MIC 4-8 ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes
Evidence 84 Activity

Activity

MIC
Antiparasitic
8->256 µg/mL

Target

Citrobacter freundii

Source & Reference

DRAMP

Other

ug/ml), A. faecalis 5 strains (MIC 4-64 ug/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25
Evidence 85 Activity

Activity

MIC
Antiparasitic
0.125-4 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

DRAMP

Other

/ml), C. diversus 10 strains (MIC 8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.fae
Evidence 86 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Enterobacter aerogenes

Source & Reference

DRAMP

Other

8-16 ug/ml), C. freundii 25 strains (MIC 8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli
Evidence 87 Activity

Activity

MIC
Antiparasitic
1-128 µg/mL

Target

Enterobacter cloacae

Source & Reference

DRAMP

Other

8->256 ug/ml), C. jeikeium (MIC 0.125-4 ug/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca
Evidence 88 Activity

Activity

MIC
Antiparasitic
>256 µg/mL

Target

Enterococcus faecalis

Source & Reference

DRAMP

Other

g/ml), E. aerogenes 25 strains (MIC 8-16 ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoni
Evidence 89 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

ug/ml), E. cloacae 25 strains (MIC 1-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. ae
Evidence 90 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Klebsiella oxytoca

Source & Reference

DRAMP

Other

-128 ug/ml), E.faecalis 30 strains (MIC >256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P.
Evidence 91 Activity

Activity

MIC
Antiparasitic
8-32 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

DRAMP

Other

>256 ug/ml), E. coli 30 strains (MIC 8-16 ug/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P.
Evidence 92 Activity

Activity

MIC
Antiparasitic
8-32 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

g/ml), K. oxytoca 10 strains (MIC 8-16 ug/ml), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aure
Evidence 93 Activity

Activity

MIC
Antiparasitic
2-8 µg/mL

Target

Pseudomonas fluorescens

Source & Reference

DRAMP

Other

l), K. pneumoniae 25 strains (MIC 8-32 ug/ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. a
Evidence 94 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Pseudomonas stutzeri

Source & Reference

DRAMP

Other

ml), P. aeruginosa 25 strains (MIC 8-32 ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/
Evidence 95 Activity

Activity

MIC
Antiparasitic
16-64 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

DRAMP

Other

ug/ml), P. fluorescens 5 strains (MIC 2-8 ug/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 u
Evidence 96 Activity

Activity

MIC
Antiparasitic
0.125-16 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

DRAMP

Other

/ml), P. stutzeri 5 strains (MIC 4-8 ug/ml), S. aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml
Evidence 97 Activity

Activity

MIC
Antiparasitic
0.125-8 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

aureus MRSA 10 strains (MIC 16-64 ug/ml), S. aureus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. sim
Evidence 98 Activity

Activity

MIC
Antiparasitic
408 µg/mL

Target

Staphylococcus haemolyticus

Source & Reference

DRAMP

Other

reus MSSA 15 strains (MIC 0.125-16 ug/ml), S. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warn
Evidence 99 Activity

Activity

MIC
Antiparasitic
2-8 µg/mL

Target

Staphylococcus hominis

Source & Reference

DRAMP

Other

. epidermidis 25 strains (MIC 0.125-8 ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S.
Evidence 100 Activity

Activity

MIC
Antiparasitic
0.125-2 µg/mL

Target

Staphylococcus simulans

Source & Reference

DRAMP

Other

ug/ml), S. haemolyticus 10 strains (MIC 408 ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less),
Evidence 101 Activity

Activity

MIC
Antiparasitic
0.125-8 µg/mL

Target

Staphylococcus warneri

Source & Reference

DRAMP

Other

ug/ml), S. hominis 5 strains (MIC 2-8 ug/ml), S. simulans 5 strains (MIC 0.125-2 ug/ml), S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml
Evidence 102 Activity

Activity

MIC
Antiparasitic
4-16 µg/mL

Target

Stenotrophomonas maltophilia

Source & Reference

DRAMP

Other

S. warneri 5 strains (MIC 0.125-8 ug/ml), S. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equi
Evidence 103 Activity

Activity

MIC
Antiparasitic
16-32 µg/mL

Target

Streptococcus agalactiae

Source & Reference

DRAMP

Other

. xylosus 1 strain (MIC 0.125 ug/ml or less), S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes
Evidence 104 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Streptococcus bovis

Source & Reference

DRAMP

Other

, S. maltophilia 10 strains (MIC 4-16 ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Strept
Evidence 105 Activity

Activity

MIC
Antiparasitic
2-16 µg/mL

Target

Streptococcus equinus

Source & Reference

DRAMP

Other

ug/ml), S. agalactiae 25 strains (MIC 16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug
Evidence 106 Activity

Activity

MIC
Antiparasitic
16-256 µg/mL

Target

Streptococcus pyogenes

Source & Reference

DRAMP

Other

16-32 ug/ml), S. bovis 5 strains (MIC 8-16 ug/ml), S. equinus 2 strains (MIC 2-16 ug/ml), S. pyogenes 30 strains (MIC 16-256 ug/ml), Streptococcus group C 5 strains (MIC 16-64 ug/ml), Streptococcus group G 5 strains (MIC
Evidence 107 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Bacteroides fragilis

Source & Reference

DRAMP

Other

/ml), Viridans group streptococci 13 strains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vu
Evidence 108 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Bacteroides ovatus

Source & Reference

DRAMP

Other

rains (MIC 4->256 ug/ml). Also anaerobic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. di
Evidence 109 Activity

Activity

MIC
Antiparasitic
0.25-0.5 µg/mL

Target

Bacteroides ureolyticus

Source & Reference

DRAMP

Other

bic bacteria: B. fragilis 6 strains (MIC 4-8 ug/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfri
Evidence 110 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

Bacteroides vulgatus

Source & Reference

DRAMP

Other

g/ml), B. ovatus 7 strains (MIC 4-8 ug/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C.
Evidence 111 Activity

Activity

MIC
Antiparasitic
0.5-4 µg/mL

Target

Clostridioides difficile

Source & Reference

DRAMP

Other

g/ml), B. ureolyticus 3 strains (MIC0.25-0.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporo
Evidence 112 Activity

Activity

MIC
Antiparasitic
8-32 µg/mL

Target

Clostridium perfringens

Source & Reference

DRAMP

Other

.5 ug/ml), B. vulgatus 6 strains (MIC 4 ug/ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridiu
Evidence 113 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

Clostridium ramosum

Source & Reference

DRAMP

Other

ml), C. difficile 4 strains (MIC 0.5-4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6
Evidence 114 Activity

Activity

MIC
Antiparasitic
8-32 µg/mL

Target

Clostridium sporogenes

Source & Reference

DRAMP

Other

4 ug/ml), C. perfringens 5 strains (MIC 8-32 ug/ml), C. ramosum 2 strains (MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharol
Evidence 115 Activity

Activity

MIC
Antiparasitic
32-64 µg/mL

Target

Peptostreptococcus anaerobius

Source & Reference

DRAMP

Other

(MIC 16 ug/ml), C. sporogenes 2 strains (MIC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml),
Evidence 116 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Peptostreptococcus asaccharolyticus

Source & Reference

DRAMP

Other

IC8-32 ug/ml), Clostridium sp. (MIC 32 ug/ml), P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. m
Evidence 117 Activity

Activity

MIC
Antiparasitic
0.5-1.0 µg/mL

Target

Peptostreptococcus magnus

Source & Reference

DRAMP

Other

P. anaerobius 6 strains (MIC 32-64 ug/ml), P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml)
Evidence 118 Activity

Activity

MIC
Antiparasitic
32-128 µg/mL

Target

Prevotella bivia

Source & Reference

DRAMP

Other

, P. asaccharolyticus 3 strains (MIC 4-8 ug/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64-
Evidence 119 Activity

Activity

MIC
Antiparasitic
32-64 µg/mL

Target

Prevotella melaninogenica

Source & Reference

DRAMP

Other

/ml), P. magnus 4 strains (MIC 0.5-1.0 ug/ml), P. bivia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histi
Evidence 120 Activity

Activity

MIC
Antiparasitic
64->512 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

ia 9 strains (MIC 32-128 ug/ml), and P. melaninogenica 3 strains (MIC 32-64 ug/ml). Also: C. albicans 10 strains (MIC 64->512 ug/ml). H. pylori. Cancer: toxic to U937 histiocytic cell line (tumor).
Evidence 121 Activity

Activity

11% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
11% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides. | Eur J Clin Microbiol Infect Dis | 2000
Evidence 122 Activity

Activity

<10% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The discovery of novel antimicrobial peptides against drug-resistant bacteria based on fragments fusion strategy | Eur J Med Chem | 2025
Evidence 123 Activity

Activity

50% Cytotoxicity
Toxicity
45.85 µg/mL
Cytotoxic
50% Cytotoxicity | 45.85 | µg/mL | target cell: Human bronchial epithelial cells BEAS-2B

Target

Human bronchial epithelial cells BEAS-2B

Source & Reference

NA
DBAASP
The discovery of novel antimicrobial peptides against drug-resistant bacteria based on fragments fusion strategy | Eur J Med Chem | 2025
Evidence 124 Activity

Activity

28% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
28% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 125 Activity

Activity

50% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
50% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides. | Antimicrob Agents Chemother | 2005
Evidence 126 Activity

Activity

50% Hemolysis
Toxicity
45 µM
Hemolytic Cytotoxic
50% Hemolysis | 45 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides. | Antimicrob Agents Chemother | 2005
Evidence 127 Activity

Activity

13% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
13% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78. | Biochim Biophys Acta | 2015
Evidence 128 Activity

Activity

25% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78. | Biochim Biophys Acta | 2015
Evidence 129 Activity

Activity

53% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
53% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78. | Biochim Biophys Acta | 2015
Evidence 130 Activity

Activity

IC50
Toxicity
1.05 µg/mL
Cytotoxic
IC50 | 1.05 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii. | Probiotics Antimicrob Proteins | 2018
Evidence 131 Activity

Activity

LD50
Toxicity
67 µg/mL
Cytotoxic
LD50 | 67 | µg/mL | target cell: Human fibroblasts WI-38

Target

Human fibroblasts WI-38

Source & Reference

NA
DBAASP
Short bioactive peptides | PATENT US 6875744B2 | 2005
Evidence 132 Activity

Activity

50% Hemolysis
Toxicity
>512 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >512 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovering highly potent antimicrobial peptides with deep generative model HydrAMP. | Nat Commun | 2023
Evidence 133 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis