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Peptide record

TPDB10029

Antibacterial Anticancer Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10029
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLRRLRDFLKKIGEKFKKIGY
Physicochemical Analysis
C126H212N36O28
ANCQHMPSTWV
K
2679.29
11.09
8
2
9
+6
4.60
-0.577
106.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
55.61
1
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
1
E
0
Q
3
G
0
H
2
I
4
L
5
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 2 L: 4 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C126H212N36O28
2679.29
11.09
+6
4.60
-0.577
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
0% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997
Evidence 2 Activity

Activity

<20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997
Evidence 3 Activity

Activity

<=50% Cell death
Toxicity
100 µM
Cytotoxic
<=50% Cell death | 100 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997