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Peptide record

TPDB10028

Antibacterial Antifungal Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10028
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FWPVVIRTVVAGYNLYRAIKKK
Physicochemical Analysis
C127H201N33O27
DCEQHMS
V
2622.20
10.95
5
0
13
+5
-0.49
0.255
115.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
8480
323.39
4
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
3
K
0
M
1
F
1
P
0
S
1
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 3 M: 0 F: 1 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 4
Chemical Descriptors
22
C127H201N33O27
2622.20
10.95
+5
-0.49
0.255
Evidence Records 4 records
Evidence 1 Activity

Activity

57% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
57% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 2 Activity

Activity

23% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
23% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 3 Activity

Activity

15% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis