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Peptide record

TPDB10027

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10027
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia SATPdb Antifungipept APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FIHHIIGWISHGVRAIHRAIHG
Physicochemical Analysis
C118H179N39O24
NDCEQLKMPTY
I
2527.97
12.40
7
0
11
+2
1.47
0.441
128.64
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
217.57
1
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
5
H
6
I
0
L
0
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 5 I: 6 L: 0 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
22
C118H179N39O24
2527.97
12.40
+2
1.47
0.441
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
1.6-0.2 µM
Hemolytic Cytotoxic
10% Hemolysis | 1.6-0.2 | µM | target cell: Cod erythrocytes

Target

Cod erythrocytes

Source & Reference

NA
DBAASP
Differential expression and biological activity of two piscidin paralogues and a novel splice variant in Atlantic cod (Gadus morhua L.). | Fish Shellfish Immunol | 2012
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.