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Peptide record

TPDB10026

Antibacterial Anticancer Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10026
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FFGRLKSVWSAVKHGWKAAKSR
Physicochemical Analysis
C120H184N36O26
NDCEQIMPTY
K
2547.01
12.44
7
0
10
+6
0.06
-0.436
57.73
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
431.88
3
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
1
L
4
K
0
M
2
F
0
P
3
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 4 M: 0 F: 2 P: 0 S: 3 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
22
C120H184N36O26
2547.01
12.44
+6
0.06
-0.436
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
800 µM
Hemolytic Cytotoxic
20% Hemolysis | 800 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Trichoplaxin - a new membrane-active antimicrobial peptide from placozoan cDNA. | Biochim Biophys Acta | 2014
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
20 %
Hemolytic Cytotoxic
Hemolytic_activity: Rat erythrocytes:20% Hemolysis=800µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2014 May 1838(5):1430-8.