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Peptide record

TPDB10025

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10025
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FFGHLYRGITSVVKHVHGLLSG
Physicochemical Analysis
C114H174N32O27
ANDCEQMPW
G
2424.83
10.42
5
0
10
+2
0.14
0.495
110.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
61.45
4
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
3
H
1
I
3
L
1
K
0
M
2
F
0
P
2
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 3 I: 1 L: 3 K: 1 M: 0 F: 2 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
22
C114H174N32O27
2424.83
10.42
+2
0.14
0.495
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5-20 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 5-20 uM), B. cereus (MIC 5-10 uM), and Psychrobacter sp.(MIC 10-15 uM). The MIC values of the form
Evidence 2 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

B. cereus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 5-20 uM), B. cereus (MIC 5-10 uM), and Psychrobacter sp.(MIC 10-15 uM). The MIC values of the former two are sensitive to t
Evidence 3 Activity

Activity

MIC
Antifungal
5-20 µM

Target

Escherichia coli

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 5-20 uM), B. cereus (MIC 5-10 uM), and Psychrobacter sp.(MIC 10-15 uM). The MIC values of the form
Evidence 4 Activity

Activity

MIC
Antifungal
5-10 µM

Target

B. cereus

Source & Reference

dbAMP Antifungipept

Other

Active against E. coli (MIC 5-20 uM), B. cereus (MIC 5-10 uM), and Psychrobacter sp.(MIC 10-15 uM). The MIC values of the former two are sensitive to t
Evidence 5 Activity

Activity

1% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
1% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A piscidin-like antimicrobial peptide from the icefish Chionodraco hamatus (Perciformes: Channichthyidae): molecular characterization, localization and bactericidal activity. | Fish Shellfish Immunol | 2012