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Peptide record

TPDB10022

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10022
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SLWETIKNAGKGFIQNILDKIR
Physicochemical Analysis
C116H190N32O32
CHMPYV
I
2544.98
10.31
4
2
9
+2
3.23
-0.305
110.91
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
216.11
5
Residue Composition
number
1
A
1
R
2
N
1
D
0
C
1
E
1
Q
2
G
0
H
4
I
2
L
3
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 1 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 4 L: 2 K: 3 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
22
C116H190N32O32
2544.98
10.31
+2
3.23
-0.305
Evidence Records 3 records
Evidence 1 Activity

Activity

22% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
22% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 2 Activity

Activity

(10.94±1.49)% Degranulation
Toxicity
50 µg/mL
Cytotoxic
(10.94±1.49)% Degranulation | 50 | µg/mL | target cell: Rat mast cells

Target

Rat mast cells

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis