Back to search

Peptide record

TPDB10008

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10008
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 22-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
DVNDLKNLCAKTHNLLPMCAMF
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C107H175N29O31S4
REQGISWY
L
2491.98
7.00
3
2
10
+0
0.82
0.173
93.18
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
125
0.05
6
Residue Composition
number
2
A
0
R
3
N
2
D
2
C
0
E
0
Q
0
G
1
H
0
I
4
L
2
K
2
M
1
F
1
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 4 K: 2 M: 2 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
22 reviewed residue count
C107H175N29O31S4 sequence-only estimate (linear, free termini)
2491.98 sequence-only estimate (linear, free termini)
7.00 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
0.82 sequence-only estimate (linear, free termini)
0.173 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cloning and expression of genes enocoding antimicrobial peptides and bradykinin from the skin and brain of Oki Tago's brown frog, Rana tagoi okiensis. | Peptides | 2010