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Peptide record

TPDB10006

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10006
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
VGRKHSILNCIPYLKKKKIMRL
Physicochemical Analysis
C120H212N36O26S2
ADEQFTW
K
2639.35
11.11
8
0
9
+7
4.59
-0.264
119.55
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
56.45
4
Residue Composition
number
0
A
2
R
1
N
0
D
1
C
0
E
0
Q
1
G
1
H
3
I
3
L
5
K
1
M
0
F
1
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 1 I: 3 L: 3 K: 5 M: 1 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
22
C120H212N36O26S2
2639.35
11.11
+7
4.59
-0.264
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 8 ug/ml), and C. albicans ATCC 14053 (MIC 8 ug/ml). Note that the mature sequence may differ from
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 8 ug/ml), and C. albicans ATCC 14053 (MIC 8 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. UPdated 7
Evidence 3 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 8 ug/ml), and C. albicans ATCC 14053 (MIC 8 ug/ml). Note that the mature sequence may differ from
Evidence 4 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 8 ug/ml), and C. albicans ATCC 14053 (MIC 8 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. UPdated 7
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016