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Peptide record

TPDB10000

Antibacterial Anticancer Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB10000
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbACP Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbACP, and other sources, with an available 3D structural model.
Sequence
RRRQRRKKRGGGDTRLNTVWMW
Physicochemical Analysis
C119H201N49O29S1
ACEHIFPSY
R
2814.28
12.80
9
1
5
+8
5.77
-2.014
30.91
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
390.86
4
Residue Composition
number
0
A
7
R
1
N
1
D
0
C
0
E
1
Q
3
G
0
H
0
I
1
L
2
K
1
M
0
F
0
P
0
S
2
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 7 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 0 S: 0 T: 2 W: 2 Y: 0 V: 1
Chemical Descriptors
22
C119H201N49O29S1
2814.28
12.80
+8
5.77
-2.014
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11-23 µM

Target

Escherichia coli

Source & Reference

NA

Other

This designed anticancer peptide also shows antimicorbial activity against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocy
Evidence 2 Activity

Activity

MIC
Antibacterial
2.9 µM

Target

A. baumannii

Source & Reference

NA

Other

gned anticancer peptide also shows antimicorbial activity against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. mal
Evidence 3 Activity

Activity

MIC
Antibacterial
23 µM

Target

E. faecium

Source & Reference

NA

Other

ty against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. ty
Evidence 4 Activity

Activity

MIC
Antibacterial
46 µM

Target

L. monocytogenes

Source & Reference

NA

Other

11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P.
Evidence 5 Activity

Activity

MIC
Antibacterial
6 µM

Target

Stenotrophomonas maltophilia

Source & Reference

NA

Other

.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
2.9 µM

Target

Streptococcus pyogenes

Source & Reference

NA

Other

M or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
23 µM

Target

S. typhimurium

Source & Reference

NA

Other

3 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
23-46 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
11-23 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

This designed anticancer peptide also shows antimicorbial activity against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocy
Evidence 10 Activity

Activity

MIC
Antifungal
2.9 µM

Target

A. baumannii

Source & Reference

Antifungipept

Other

gned anticancer peptide also shows antimicorbial activity against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. mal
Evidence 11 Activity

Activity

MIC
Antifungal
23 µM

Target

E. faecium

Source & Reference

Antifungipept

Other

ty against E. coli (MIC 11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. ty
Evidence 12 Activity

Activity

MIC
Antifungal
46 µM

Target

L. monocytogenes

Source & Reference

Antifungipept

Other

11-23 uM), A. baumannii (MIC 2.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P.
Evidence 13 Activity

Activity

MIC
Antifungal
6 µM

Target

Stenotrophomonas maltophilia

Source & Reference

Antifungipept

Other

.9 uM), S. aureus (MIC 46 uM or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 14 Activity

Activity

MIC
Antifungal
2.9 µM

Target

Streptococcus pyogenes

Source & Reference

Antifungipept

Other

M or >), E. faecium (MIC 23 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 15 Activity

Activity

MIC
Antifungal
23 µM

Target

S. typhimurium

Source & Reference

Antifungipept

Other

3 uM), L. monocytogenes (MIC 46 uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 16 Activity

Activity

MIC
Antifungal
23-46 µM

Target

Pseudomonas aeruginosa

Source & Reference

Antifungipept

Other

uM), S. maltophilia (MIC 6 uM), S. pyogenes (MIC 2.9 uM), S. typhimurium (MIC 23 uM), and P. aeruginosa (MIC 23-46 uM).
Evidence 17 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Front Microbiol. 2017 Jun 7 8:994.