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Peptide record

TPDB09987

Antibacterial Antifungal Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09987
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FFGSTIGALANFLPSLISKIRN
Physicochemical Analysis
C111H176N28O29
DCEQHMWYV
ILFS
2366.79
11.49
2
0
11
+2
-2.70
0.727
115.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
6
Residue Composition
number
2
A
1
R
2
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
3
L
1
K
0
M
3
F
1
P
3
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 1 M: 0 F: 3 P: 1 S: 3 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C111H176N28O29
2366.79
11.49
+2
-2.70
0.727
Evidence Records 6 records
Evidence 1 Activity

Activity

13.1% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
13.1% Hemolysis | 32 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 2 Activity

Activity

54.7% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
54.7% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 3 Activity

Activity

90.1% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
90.1% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 4 Activity

Activity

87% Killing
Toxicity
32 µg/mL
Cytotoxic
87% Killing | 32 | µg/mL | target cell: Monkey COS-7 cells

Target

Monkey COS-7 cells

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 5 Activity

Activity

100% Killing
Toxicity
64 µg/mL
Cytotoxic
100% Killing | 64 | µg/mL | target cell: Monkey COS-7 cells

Target

Monkey COS-7 cells

Source & Reference

NA
DBAASP
Molecular Cloning and Functional Characterization of Antimicrobial Peptides Brevinin-1ULf and Ulmin-1ULa in the Skin of the Newly Classified Ryukyu Brown Frog Rana ulma. | Zoolog Sci | 2017
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis