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Peptide record

TPDB09984

Antibacterial Anticancer Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09984
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KILGVSKKIMRRISKDILTGKK
Physicochemical Analysis
C112H210N34O28S1
ANCEQHFPWY
K
2513.17
11.72
8
1
8
+7
6.69
-0.332
119.55
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
4
I
2
L
6
K
1
M
0
F
0
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 2 K: 6 M: 1 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C112H210N34O28S1
2513.17
11.72
+7
6.69
-0.332
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens. | J Biol Chem | 2007
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <5% Hemolysis=100 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2007 May 18 282(20):14719-28.