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Peptide record

TPDB09968

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09968
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FPFLKLSLKIPKSAIKSAIKRL
Physicochemical Analysis
C121H208N30O26
NDCEQGHMTWYV
K
2499.17
11.85
6
0
11
+6
1.28
0.377
133.18
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
4
L
5
K
0
M
2
F
2
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 4 K: 5 M: 0 F: 2 P: 2 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C121H208N30O26
2499.17
11.85
+6
1.28
0.377
Evidence Records 4 records
Evidence 1 Activity

Activity

EC50
Toxicity
141.40 µM
Cytotoxic
EC50 | 141.40 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
149.75 µM
Hemolytic Cytotoxic
10% Hemolysis | 149.75 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
1726 µM
Hemolytic Cytotoxic
50% Hemolysis | 1726 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
19894.17 µM
Hemolytic Cytotoxic
90% Hemolysis | 19894.17 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017