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Peptide record

TPDB09946

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09946
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 22-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
NVLKKLNRLKEKNKAKNSKENN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C111H200N38O34
DCQGHIMFPTWY
K
2611.04
10.91
8
2
5
+6
4.09
-1.964
70.91
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
7
Residue Composition
number
1
A
1
R
6
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
3
L
7
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 6 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 7 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22 reviewed residue count
C111H200N38O34 sequence-only estimate (linear, free termini)
2611.04 sequence-only estimate (linear, free termini)
10.91 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
4.09 sequence-only estimate (linear, free termini)
-1.964 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 512 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Distinctin-Like-Peptide-PH (DLP-PH) From the Skin Secretion of Phyllomedusa hypochondrialis, a Prototype of a Novel Family of Antimicrobial Peptide. | Front Microbiol | 2018