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Peptide record

TPDB09944

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09944
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 22-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RVVRQWPIGRVVRRVVRRVVRL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C123H220N48O24
ANDCEHKMFSTY
RV
2755.41
13.25
8
0
11
+8
3.61
-0.023
140.91
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
2.00
1
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 8
Chemical Descriptors
22 reviewed residue count
C123H220N48O24 sequence-only estimate (linear, free termini)
2755.41 sequence-only estimate (linear, free termini)
13.25 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
3.61 sequence-only estimate (linear, free termini)
-0.023 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Display of multimeric antimicrobial peptides on the Escherichia coli cell surface and its application as whole-cell antibiotics. | PLoS One | 2013