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Peptide record

TPDB09939

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09939
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFHHIFRGIVHVGKKIHRLVTG
Physicochemical Analysis
C124H192N38O24
ANDCEQMPSWY
H
2599.13
12.42
8
0
10
+4
2.94
0.309
110.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
3
I
1
L
2
K
0
M
3
F
0
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 3 L: 1 K: 2 M: 0 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C124H192N38O24
2599.13
12.42
+4
2.94
0.309
Evidence Records 2 records
Evidence 1 Activity

Activity

55% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
55% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. | Sci Rep | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
46 µM
Hemolytic Cytotoxic
50% Hemolysis | 46 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. | Sci Rep | 2017