Peptide record

TPDB09924

Antibacterial Anticancer Antifungal Antiparasitic standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09924
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FKSWSFCTPGCAKTGSFNSYCC
Physicochemical Analysis
C107H150N26O31S4
RDEQHILMV
CS
2424.76
8.30
2
0
6
+2
-3.64
-0.014
4.55
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
7240
298.59
12
Residue Composition
number
1
A
0
R
1
N
0
D
4
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
3
F
1
P
4
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 3 P: 1 S: 4 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
22
C107H150N26O31S4
2424.76
8.30
+2
-3.64
-0.014
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.2 µg/mL

Target

P. acnes

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
s spp., C. diphtheriae (MIC 0.4-1.6), G. vaginalis (MIC 0.03), M. smegmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune
Evidence 2 Activity

Activity

MIC
Antibacterial
49.2 µg/mL

Target

B. bronchiseptica

Source & Reference

dbAMP DRAMP

Other

egmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria
Evidence 3 Activity

Activity

MIC
Antibacterial
0.07 µg/mL

Target

C. jejune

Source & Reference

dbAMP DRAMP

Other

1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria spp (MIC 1.6).
Evidence 4 Activity

Activity

MIC
Antifungal
1.2 µg/mL

Target

P. acnes

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
s spp., C. diphtheriae (MIC 0.4-1.6), G. vaginalis (MIC 0.03), M. smegmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune
Evidence 5 Activity

Activity

MIC
Antifungal
49.2 µg/mL

Target

B. bronchiseptica

Source & Reference

dbAMP DRAMP Antifungipept

Other

egmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria
Evidence 6 Activity

Activity

MIC
Antifungal
0.07 µg/mL

Target

C. jejune

Source & Reference

dbAMP DRAMP Antifungipept

Other

1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria spp (MIC 1.6).
Evidence 7 Activity

Activity

MIC
Antiparasitic
1.2 µg/mL

Target

P. acnes

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
s spp., C. diphtheriae (MIC 0.4-1.6), G. vaginalis (MIC 0.03), M. smegmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune
Evidence 8 Activity

Activity

MIC
Antiparasitic
49.2 µg/mL

Target

B. bronchiseptica

Source & Reference

DRAMP

Other

egmatis (MIC 32), and P. acnes (MIC 1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria
Evidence 9 Activity

Activity

MIC
Antiparasitic
0.07 µg/mL

Target

C. jejune

Source & Reference

DRAMP

Other

1.2 ug/ml). Also, active also against Gram- bacteria: B. bronchiseptica (MIC 49.2 ug/ml), C. jejune (MIC 0.07 ug/ml), H. influenzae (MIC 13), H. pylori (MIC 0.07), and Neisseria spp (MIC 1.6).