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Peptide record

TPDB09922

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09922
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
TISQPEWFKARRWQWRMKKLGA
Physicochemical Analysis
C130H199N39O29S1
NDCHYV
RKW
2804.31
12.14
6
1
9
+5
1.19
-1.150
44.55
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
16500
588.38
4
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
1
E
2
Q
1
G
0
H
1
I
1
L
3
K
1
M
1
F
1
P
1
S
1
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 1 L: 1 K: 3 M: 1 F: 1 P: 1 S: 1 T: 1 W: 3 Y: 0 V: 0
Chemical Descriptors
22
C130H199N39O29S1
2804.31
12.14
+5
1.19
-1.150
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
1% Hemolysis | 400 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Designed low amphipathic peptides with alpha-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanism. | Peptides | 2010