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Peptide record

TPDB09919

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09919
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KFHHIFRGIVHVGKTIHRLVTG
Physicochemical Analysis
C119H190N38O25
ANDCEQMPSWY
H
2553.06
12.42
8
0
9
+4
4.21
0.150
110.45
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
3
I
1
L
2
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C119H190N38O25
2553.06
12.42
+4
4.21
0.150
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Role of phenylalanine and valine10 residues in the antimicrobial activity and cytotoxicity of piscidin-1. | PLoS One | 2014
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis