Peptide record

TPDB09913

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09913
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFHHIWRGIVHVGKTIHRLVTG
Physicochemical Analysis
C124H188N38O25
ANDCEQMPSY
H
2611.10
12.41
7
0
10
+3
1.37
0.286
110.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
210.64
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
3
I
1
L
1
K
0
M
2
F
0
P
0
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 3 L: 1 K: 1 M: 0 F: 2 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
22
C124H188N38O25
2611.10
12.41
+3
1.37
0.286
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
3.2 µM
Hemolytic Cytotoxic
<5% Hemolysis | 3.2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Role of phenylalanine and valine10 residues in the antimicrobial activity and cytotoxicity of piscidin-1. | PLoS One | 2014