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Peptide record

TPDB09904

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB09904
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
TIAMRAINNYRWRSKNQNTFLR
Physicochemical Analysis
C120H193N41O32S1
DCEGHPV
RN
2754.17
12.41
5
0
9
+5
1.23
-1.032
62.27
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
6990
253.80
9
Residue Composition
number
2
A
4
R
4
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
1
K
1
M
1
F
0
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 4 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 1 M: 1 F: 1 P: 0 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
22
C120H193N41O32S1
2754.17
12.41
+5
1.23
-1.032
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
18.7±0.1 µM
Hemolytic Cytotoxic
50% Hemolysis | 18.7±0.1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Refining the eosinophil cationic protein antibacterial pharmacophore by rational structure minimization. | J Med Chem | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis