Back to search

Peptide record

TPDB09902

Antibacterial Anticancer Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09902
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
LLGAALSALSSVIPSVISWFQK
Physicochemical Analysis
C108H175N25O29
RNDCEHMTY
S
2287.73
10.10
1
0
13
+1
-3.53
1.205
146.36
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
240.41
6
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
2
I
4
L
1
K
0
M
1
F
1
P
5
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 4 K: 1 M: 0 F: 1 P: 1 S: 5 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
22
C108H175N25O29
2287.73
10.10
+1
-3.53
1.205
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4-16 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

Active against S. aureus ATCC 29213 (MIC 4-16 uM) and E-coli (MIC >64 uM) evaluated using microdilution assay in MH medium. Active against
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

NA

Other

and E-coli (MIC >64 uM) evaluated using microdilution assay in MH medium. Active against E. faecalis ATCC 29212 (MIC 16 uM), and A. baumannii ATCC 19606 (MIC 32 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
32 µM

Target

A. baumannii ATCC 19606

Source & Reference

NA

Other

microdilution assay in MH medium. Active against E. faecalis ATCC 29212 (MIC 16 uM), and A. baumannii ATCC 19606 (MIC 32 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
4-16 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

Antifungipept

Other

Active against S. aureus ATCC 29213 (MIC 4-16 uM) and E-coli (MIC >64 uM) evaluated using microdilution assay in MH medium. Active against
Evidence 5 Activity

Activity

MIC
Antifungal
16 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

Antifungipept

Other

and E-coli (MIC >64 uM) evaluated using microdilution assay in MH medium. Active against E. faecalis ATCC 29212 (MIC 16 uM), and A. baumannii ATCC 19606 (MIC 32 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
32 µM

Target

A. baumannii ATCC 19606

Source & Reference

Antifungipept

Other

microdilution assay in MH medium. Active against E. faecalis ATCC 29212 (MIC 16 uM), and A. baumannii ATCC 19606 (MIC 32 uM).
Evidence 7 Activity

Activity

<20% Killing
Toxicity
100 µM
Cytotoxic
<20% Killing | 100 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Membrane-active antimicrobial peptide identified in Rana arvalis by targeted DNA sequencing. | Biochim Biophys Acta | 2018
Evidence 8 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta Biomembr. 2019 Mar 1 1861(3):651-659.