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Peptide record

TPDB09899

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09899
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FIHHIIGGLFHVGKSIHDLIR
Physicochemical Analysis
C114H177N33O25
ANCEQMPTWY
I
2409.87
10.09
6
1
10
+1
2.17
0.629
143.81
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
3
G
4
H
5
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 5 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C114H177N33O25
2409.87
10.09
+1
2.17
0.629
Evidence Records 6 records
Evidence 1 Activity

Activity

>60% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
>60% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018
Evidence 3 Activity

Activity

97% Hemolysis
Toxicity
100-200 µM
Hemolytic Cytotoxic
97% Hemolysis | 100-200 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018
Evidence 4 Activity

Activity

>60% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
>60% Hemolysis | 200 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018
Evidence 5 Activity

Activity

>90% Hemolysis
Toxicity
>50 µM
Hemolytic Cytotoxic
>90% Hemolysis | >50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018
Evidence 6 Activity

Activity

>90% Hemolysis
Toxicity
>50 µM
Hemolytic Cytotoxic
>90% Hemolysis | >50 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-?. | Fish Shellfish Immunol | 2018