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Peptide record

TPDB09892

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09892
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LGGGLAANFLPQILCKIARKC
Physicochemical Analysis
C98H168N28O24S2
DEHMSTWYV
L
2186.70
9.92
3
0
10
+3
-0.71
0.729
125.71
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
5.72
4
Residue Composition
number
3
A
1
R
1
N
0
D
2
C
0
E
1
Q
3
G
0
H
2
I
4
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 3 H: 0 I: 2 L: 4 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C98H168N28O24S2
2186.70
9.92
+3
-0.71
0.729
Evidence Records 1 records
Evidence 1 Activity

Activity

23.4% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
23.4% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship and Mode of Action of a Frog Secreted Antibacterial Peptide B1CTcu5 Using Synthetically and Modularly Modified or Deleted (SMMD) Peptides. | PLoS One | 2015