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Peptide record

TPDB09879

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09879
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
APPGARPPPGPPPPGPPPPGP
Physicochemical Analysis
C90H134N24O22
NDCEQHILKMFSTWYV
P
1904.20
11.05
1
0
2
+1
6.81
-1.186
9.52
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
0
F
14
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 14 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C90H134N24O22
1904.20
11.05
+1
6.81
-1.186
Evidence Records 9 records
Evidence 1 Activity

Activity

EC50
Antibacterial
58.68 µM

Target

A. fumigatus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µM

Target

C. neoformans AIDS 25

Source & Reference

dbAMP

Other

st fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 3 Activity

Activity

EC50
Antifungal
58.68 µM

Target

A. fumigatus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
100 µM

Target

C. neoformans AIDS 25

Source & Reference

dbAMP CAFPdb Antifungipept

Other

st fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 5 Activity

Activity

EC50
Antiparasitic
58.68 µM

Target

A. fumigatus

Source & Reference

NA

Other

Active against fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antiparasitic
100 µM

Target

C. neoformans AIDS 25

Source & Reference

NA

Other

st fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 7 Activity

Activity

EC50
Antiviral
58.68 µM

Target

A. fumigatus

Source & Reference

NA

Other

Active against fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 8 Activity

Activity

MIC
Antiviral
100 µM

Target

C. neoformans AIDS 25

Source & Reference

NA

Other

st fungi C. albicans UP10 (EC50 34.69 uM, MIC 13.1 uM), A. fumigatus (EC50 58.68 uM), and C. neoformans AIDS 25 (MIC 100 uM). Updated 7/2021
Evidence 9 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse fibroblasts 3T3-Swiss cell line

Target

Mouse fibroblasts 3T3-Swiss cell line

Source & Reference

NA
DBAASP
Structural and functional characterization of the porcine proline-rich antifungal peptide SP-B isolated from salivary gland granules. | J Pept Sci | 2008