Back to search

Peptide record

TPDB09875

Antibacterial Antifungal Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09875
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFMKYIGPLIPHAVKAISKLI
Physicochemical Analysis
C111H182N26O24S1
RNDCEQTW
I
2296.89
10.46
4
0
12
+3
0.05
0.814
134.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
64.87
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
4
I
2
L
3
K
1
M
1
F
2
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 4 L: 2 K: 3 M: 1 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C111H182N26O24S1
2296.89
10.46
+3
0.05
0.814
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
45 µM
Hemolytic Cytotoxic
50% Hemolysis | 45 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. | Peptides | 2005
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
120 µM
Hemolytic Cytotoxic
50% Hemolysis | 120 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. | Peptides | 2005
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis