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Peptide record

TPDB09873

Antibacterial Antifungal Antiparasitic Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09873
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SIGRRGGYCAGIIKQTCTCYR
Physicochemical Analysis
C96H160N32O28S3
NDEHLMFPWV
G
2306.70
9.64
4
0
6
+4
0.75
-0.214
60.48
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
3105
134.61
9
Residue Composition
number
1
A
3
R
0
N
0
D
3
C
0
E
1
Q
4
G
0
H
3
I
0
L
1
K
0
M
0
F
0
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 3 E: 0 Q: 1 G: 4 H: 0 I: 3 L: 0 K: 1 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
21
C96H160N32O28S3
2306.70
9.64
+4
0.75
-0.214
Evidence Records 6 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Babesial vector tick defensin against Babesia sp. parasites. | Infect Immun | 2007
Evidence 2 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Babesial vector tick defensin against Babesia sp. parasites. | Infect Immun | 2007
Evidence 3 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Structural characterization and cytolytic activity of a potent antimicrobial motif in longicin, a defensin-like peptide in the tick Haemaphysalis longicornis. | J Vet Med Sci | 2010
Evidence 4 Activity

Activity

4% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
4% Hemolysis | 250 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
Structural characterization and cytolytic activity of a potent antimicrobial motif in longicin, a defensin-like peptide in the tick Haemaphysalis longicornis. | J Vet Med Sci | 2010
Evidence 5 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Cattle erythrocytes

Target

Cattle erythrocytes

Source & Reference

NA
DBAASP
Structural characterization and cytolytic activity of a potent antimicrobial motif in longicin, a defensin-like peptide in the tick Haemaphysalis longicornis. | J Vet Med Sci | 2010
Evidence 6 Activity

Activity

40% Inhibition
Toxicity
16 µM
Cytotoxic
40% Inhibition | 16 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Structural characterization and cytolytic activity of a potent antimicrobial motif in longicin, a defensin-like peptide in the tick Haemaphysalis longicornis. | J Vet Med Sci | 2010