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Peptide record

TPDB09858

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09858
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLSGILGAGKNIVCGLSGLC
Physicochemical Analysis
C84H149N23O25S2
RDEQHMFPTWY
G
1945.37
8.29
1
0
9
+1
-2.27
1.314
148.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
6.43
5
Residue Composition
number
1
A
0
R
1
N
0
D
2
C
0
E
0
Q
6
G
0
H
2
I
5
L
1
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 5 K: 1 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C84H149N23O25S2
1945.37
8.29
+1
-2.27
1.314
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.aureus NCTC 8325

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

C.albicans ATCC 90028

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.aureus NCTC 8325

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µM

Target

C.albicans ATCC 90028

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Escherichia coli ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 8 Activity

Activity

MIC
Antiparasitic
>100 µM

Target

S.aureus NCTC 8325

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µM

Target

C.albicans ATCC 90028

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 50 uM), S.aureus NCTC 8325 (MIC >100 uM) and C.albicans ATCC 90028 (MIC >100 uM).
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
295 µM
Hemolytic Cytotoxic
50% Hemolysis | 295 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami. | Peptides | 2006
Evidence 11 Activity

Activity

LC50
Toxicity
500 µM
Hemolytic
Hemolytic_activity: [Ref:16621155] LC50>500 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2006 Sep 27(9):2111-2117.