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Peptide record

TPDB09857

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09857
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILSGVLGMGKKIVCGLSGLC
Physicochemical Analysis
C87H157N23O24S3
ARNDEQHFPTWY
G
2005.52
9.11
2
0
9
+2
-1.13
1.319
139.05
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
6.23
4
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
6
G
0
H
2
I
4
L
2
K
1
M
0
F
0
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 4 K: 2 M: 1 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
21
C87H157N23O24S3
2005.52
9.11
+2
-1.13
1.319
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
8.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al.
Evidence 3 Activity

Activity

MIC
Antibacterial
4.4 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 4 Activity

Activity

MIC
Antifungal
4.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
8.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al.
Evidence 6 Activity

Activity

MIC
Antifungal
4.4 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 7 Activity

Activity

MIC
Antiparasitic
4.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
8.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al.
Evidence 9 Activity

Activity

MIC
Antiparasitic
4.4 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 10 Activity

Activity

MIC
Antiviral
4.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
8.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al.
Evidence 12 Activity

Activity

MIC
Antiviral
4.4 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.8 ug/ml), Gram+ bacteria S. aureus (MIC 8.8 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1