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Peptide record

TPDB09852

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09852
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia SATPdb AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFWGKLFKLGLHGIGLLHLHL
Physicochemical Analysis
C117H178N30O22
ARNDCEQMPSTYV
L
2356.89
10.60
5
0
11
+2
-3.43
0.781
148.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
233.36
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
3
H
1
I
7
L
2
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 3 I: 1 L: 7 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C117H178N30O22
2356.89
10.60
+2
-3.43
0.781
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 2 Activity

Activity

>10% Killing
Toxicity
1 µM
Cytotoxic
>10% Killing | 1 | µM | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 3 Activity

Activity

>10% Killing
Toxicity
5 µM
Cytotoxic
>10% Killing | 5 | µM | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 4 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.