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Peptide record

TPDB09845

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09845
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept CAFPdb i2APP AI4AVP ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GSKKPVPIIYCNRRTGKCQRM
Physicochemical Analysis
C103H179N35O27S3
ADEHLFW
RK
2435.95
10.88
6
0
5
+6
5.39
-0.900
50.95
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
66.30
7
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
2
G
0
H
2
I
0
L
3
K
1
M
0
F
2
P
1
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 0 K: 3 M: 1 F: 0 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C103H179N35O27S3
2435.95
10.88
+6
5.39
-0.900
Evidence Records 78 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.6-1.2 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-
Evidence 2 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acid
Evidence 3 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram-
Evidence 4 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S
Evidence 5 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

P. acidolactici

Source & Reference

dbAMP DRAMP

Other

2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1
Evidence 6 Activity

Activity

MIC
Antibacterial
0.3-1.2 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5
Evidence 7 Activity

Activity

MIC
Antibacterial
0.6-1.2 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM)
Evidence 8 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

Enterobacter cloacae

Source & Reference

dbAMP DRAMP

Other

E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2
Evidence 9 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

E. carotovora

Source & Reference

dbAMP DRAMP

Other

typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 u
Evidence 10 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2
Evidence 11 Activity

Activity

MIC
Antibacterial
0.6-1.2 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP

Other

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM)
Evidence 12 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP

Other

arotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 u
Evidence 13 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

N. haematococca

Source & Reference

dbAMP DRAMP

Other

aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A.
Evidence 14 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

T. viride

Source & Reference

dbAMP DRAMP

Other

N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F.
Evidence 15 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

A. brassicola

Source & Reference

dbAMP DRAMP

Other

N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 16 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

F. culmorum

Source & Reference

dbAMP DRAMP

Other

haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 17 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

A. pisi

Source & Reference

dbAMP DRAMP

Other

M), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 18 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 19 Activity

Activity

MIC
Antifungal
0.6-1.2 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-
Evidence 20 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acid
Evidence 21 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram-
Evidence 22 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S
Evidence 23 Activity

Activity

MIC
Antifungal
20-40 µM

Target

P. acidolactici

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1
Evidence 24 Activity

Activity

MIC
Antifungal
0.3-1.2 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5
Evidence 25 Activity

Activity

MIC
Antifungal
0.6-1.2 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM)
Evidence 26 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

Enterobacter cloacae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2
Evidence 27 Activity

Activity

MIC
Antifungal
10-20 µM

Target

E. carotovora

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 u
Evidence 28 Activity

Activity

MIC
Antifungal
20-40 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2
Evidence 29 Activity

Activity

MIC
Antifungal
0.6-1.2 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM)
Evidence 30 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

arotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 u
Evidence 31 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

N. haematococca

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A.
Evidence 32 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

T. viride

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F.
Evidence 33 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

A. brassicola

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 34 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

F. culmorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 35 Activity

Activity

MIC
Antifungal
5-10 µM

Target

A. pisi

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

M), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 36 Activity

Activity

MIC
Antifungal
10-20 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 37 Activity

Activity

MIC
Antiparasitic
0.6-1.2 µM

Target

A. viridans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-
Evidence 38 Activity

Activity

MIC
Antiparasitic
1.2-2.5 µM

Target

M. luteus

Source & Reference

DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acid
Evidence 39 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

B. megaterium

Source & Reference

DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram-
Evidence 40 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S
Evidence 41 Activity

Activity

MIC
Antiparasitic
20-40 µM

Target

P. acidolactici

Source & Reference

DRAMP

Other

2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1
Evidence 42 Activity

Activity

MIC
Antiparasitic
0.3-1.2 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5
Evidence 43 Activity

Activity

MIC
Antiparasitic
0.6-1.2 µM

Target

S. typhimurium

Source & Reference

DRAMP

Other

), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM)
Evidence 44 Activity

Activity

MIC
Antiparasitic
1.2-2.5 µM

Target

Enterobacter cloacae

Source & Reference

DRAMP

Other

E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2
Evidence 45 Activity

Activity

MIC
Antiparasitic
10-20 µM

Target

E. carotovora

Source & Reference

DRAMP

Other

typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 u
Evidence 46 Activity

Activity

MIC
Antiparasitic
20-40 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2
Evidence 47 Activity

Activity

MIC
Antiparasitic
0.6-1.2 µM

Target

N. crassa

Source & Reference

DRAMP

Other

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM)
Evidence 48 Activity

Activity

MIC
Antiparasitic
1.2-2.5 µM

Target

N. crassa

Source & Reference

DRAMP

Other

arotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 u
Evidence 49 Activity

Activity

MIC
Antiparasitic
1.2-2.5 µM

Target

N. haematococca

Source & Reference

DRAMP

Other

aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A.
Evidence 50 Activity

Activity

MIC
Antiparasitic
1.2-2.5 µM

Target

T. viride

Source & Reference

DRAMP

Other

N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F.
Evidence 51 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

A. brassicola

Source & Reference

DRAMP

Other

N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 52 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

F. culmorum

Source & Reference

DRAMP

Other

haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 53 Activity

Activity

MIC
Antiparasitic
5-10 µM

Target

A. pisi

Source & Reference

DRAMP

Other

M), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 54 Activity

Activity

MIC
Antiparasitic
10-20 µM

Target

F. oxysporum

Source & Reference

DRAMP

Other

uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 55 Activity

Activity

MIC
Antiviral
0.6-1.2 µM

Target

A. viridans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-
Evidence 56 Activity

Activity

MIC
Antiviral
1.2-2.5 µM

Target

M. luteus

Source & Reference

DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acid
Evidence 57 Activity

Activity

MIC
Antiviral
2.5-5 µM

Target

B. megaterium

Source & Reference

DRAMP

Other

Active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram-
Evidence 58 Activity

Activity

MIC
Antiviral
2.5-5 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S
Evidence 59 Activity

Activity

MIC
Antiviral
20-40 µM

Target

P. acidolactici

Source & Reference

DRAMP

Other

2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1
Evidence 60 Activity

Activity

MIC
Antiviral
0.3-1.2 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

B. subtilis (MIC 2.5-5 uM), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5
Evidence 61 Activity

Activity

MIC
Antiviral
0.6-1.2 µM

Target

S. typhimurium

Source & Reference

DRAMP

Other

), S-aureus (MIC >40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM)
Evidence 62 Activity

Activity

MIC
Antiviral
1.2-2.5 µM

Target

Enterobacter cloacae

Source & Reference

DRAMP

Other

E. coli (MIC 0.3-1.2 uM), S. typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2
Evidence 63 Activity

Activity

MIC
Antiviral
10-20 µM

Target

E. carotovora

Source & Reference

DRAMP

Other

typhimurium (MIC 0.6-1.2 uM), K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 u
Evidence 64 Activity

Activity

MIC
Antiviral
20-40 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

K pneumoniae (MIC 0.6-1.2 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2
Evidence 65 Activity

Activity

MIC
Antiviral
0.6-1.2 µM

Target

N. crassa

Source & Reference

DRAMP

Other

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM)
Evidence 66 Activity

Activity

MIC
Antiviral
1.2-2.5 µM

Target

N. crassa

Source & Reference

DRAMP

Other

arotovora (MIC 10-20 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 u
Evidence 67 Activity

Activity

MIC
Antiviral
1.2-2.5 µM

Target

N. haematococca

Source & Reference

DRAMP

Other

aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A.
Evidence 68 Activity

Activity

MIC
Antiviral
1.2-2.5 µM

Target

T. viride

Source & Reference

DRAMP

Other

N. crassa (MIC 0.6-1.2 uM), N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F.
Evidence 69 Activity

Activity

MIC
Antiviral
2.5-5 µM

Target

A. brassicola

Source & Reference

DRAMP

Other

N. crassa (MIC 1.2-2.5 uM), N. haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 70 Activity

Activity

MIC
Antiviral
2.5-5 µM

Target

F. culmorum

Source & Reference

DRAMP

Other

haematococca (MIC 1.2-2.5 uM), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 71 Activity

Activity

MIC
Antiviral
5-10 µM

Target

A. pisi

Source & Reference

DRAMP

Other

M), T. viride (MIC 1.2-2.5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 72 Activity

Activity

MIC
Antiviral
10-20 µM

Target

F. oxysporum

Source & Reference

DRAMP

Other

uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 2.5-5 uM), A. pisi (MIC 5-10 uM), and F. oxysporum (MIC 10-20 uM).
Evidence 73 Activity

Activity

0% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
0% Hemolysis | 40 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides. | Proc Natl Acad Sci U S A | 1996
Evidence 74 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 75 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
The Disulfide Bond of the Peptide Thanatin Is Dispensible for Its Antimicrobial Activity In Vivo and In Vitro. | Antimicrob Agents Chemother | 2016
Evidence 76 Activity

Activity

1.3±0.4% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
1.3±0.4% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides. | ACS Infect Dis | 2016
Evidence 77 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Disulfide Bond of the Peptide Thanatin Is Dispensible for Its Antimicrobial Activity In Vivo and In Vitro. | Antimicrob Agents Chemother | 2016
Evidence 78 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.8577744] It exhibits no hemolytic activity at 40 µM against porcine erythrocytes.

Target

erythrocytes

Source & Reference

NA
DRAMP
Proc Natl Acad Sci U S A. 1996 Feb 6 93(3):1221-1225.##Eur J Biochem. 1998 Sep 1 256(2):404-410.