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Peptide record

TPDB09830

Antibacterial Antifungal Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09830
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 21-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RVVRQWPIGRVVRRVVRRVVR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C117H209N47O23
ANDCEHLKMFSTY
RV
2642.25
13.25
8
0
10
+8
4.02
-0.205
129.05
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
2.08
1
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 8
Chemical Descriptors
21 reviewed residue count
C117H209N47O23 sequence-only estimate (linear, free termini)
2642.25 sequence-only estimate (linear, free termini)
13.25 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
4.02 sequence-only estimate (linear, free termini)
-0.205 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
>200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | >200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Display of multimeric antimicrobial peptides on the Escherichia coli cell surface and its application as whole-cell antibiotics. | PLoS One | 2013