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Peptide record

TPDB09818

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09818
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GMASKAGSVLGKITKIALGAL
Physicochemical Analysis
C88H160N24O25S1
RNDCEQHFPWY
AG
1986.44
10.84
3
0
11
+3
0.27
0.862
125.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
2
I
3
L
3
K
1
M
0
F
0
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 3 K: 3 M: 1 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C88H160N24O25S1
1986.44
10.84
+3
0.27
0.862
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
100 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
50 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 8 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Candida albicans

Source & Reference

NA

Other

Active against E. coli (MIC 12.5 uM), S. aureus (MIC 100 uM), and C. albicans (MIC 50 uM).
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific. | Peptides | 2011