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Peptide record

TPDB09815

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB09815
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIFGKILGVGKKVLCGLSGWC
Physicochemical Analysis
C99H163N25O23S2
ARNDEQHMPTY
G
2135.66
9.80
3
0
9
+3
-2.46
0.990
120.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
263.39
3
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
6
G
0
H
2
I
3
L
3
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 3 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
21
C99H163N25O23S2
2135.66
9.80
+3
-2.46
0.990
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
23.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml)
Evidence 2 Activity

Activity

MIC
Antibacterial
5.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 3 Activity

Activity

MIC
Antibacterial
5.9 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 4 Activity

Activity

MIC
Antibacterial
11.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

nst E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 5 Activity

Activity

MIC
Antifungal
23.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml)
Evidence 6 Activity

Activity

MIC
Antifungal
5.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 7 Activity

Activity

MIC
Antifungal
5.9 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 8 Activity

Activity

MIC
Antifungal
11.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

nst E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 9 Activity

Activity

MIC
Antiparasitic
23.6 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml)
Evidence 10 Activity

Activity

MIC
Antiparasitic
5.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 11 Activity

Activity

MIC
Antiparasitic
5.9 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 12 Activity

Activity

MIC
Antiparasitic
11.8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

nst E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 13 Activity

Activity

MIC
Antiviral
23.6 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml)
Evidence 14 Activity

Activity

MIC
Antiviral
5.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 15 Activity

Activity

MIC
Antiviral
5.9 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 16 Activity

Activity

MIC
Antiviral
11.8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

nst E. coli (MIC 23.6 ug/ml), S. aureus (MIC 5.9 ug/ml), B. subtilis (MIC 5.9 ug/ml), and C. albicans (MIC 11.8 ug/ml). Aslo histamine release.
Evidence 17 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.